Description of work (possibly broken down into tasks), and role of participants

·         Task 1. Maximum Tolerated Dose (acute toxicity).

·         Task 2. In vivo Test I: Parasitaemia reduction in the acute phase.

·         Task 3. In vivo Test II: Cure in the acute phase.

·         Task 4. In vivo Test III: Cure in the acute phase using resistant strains.

·         Task 5. Induction of the murine Chronic Phase of Chagas disease.

Task 6. Other in vivo test